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 Juri Gelovani

President of WMIS

Juri Gelovani was born in 1964 in Tbilisi, Republic of Georgia and graduated a high school in 1980. In 1986, he graduated a medical school (MD) of the University of Tartu, Estonia, and pursued postgraduate training in Neurosurgery. In 1990, he defended a dual-specialty clinical research based dissertation in Neurosurgery and Neuroradiology (PhD). In 1991, he joined as a post-doctoral fellow at the Department of Neurology, Memorial Sloan Kettering Cancer Center. Dr. Gelovani’s initial work (1991-1993) was focused on imaging brain tumor proliferative activity and brain tumor gene therapy. During 1992-1993, he developed and validated the original idea for non-invasive radiotracer-based in vivo imaging of the location, magnitude, and duration of the HSV1-tk reporter/therapeutic gene in the whole body. In 1995, his paper (Cancer Res., 55:6121-6135, 1995) started the field of “molecular-genetic imaging”. Since, Dr. Gelovani has published several original papers which further expanded the spectrum of various reporter gene imaging systems and novel radiolabeled agents for PET imaging for applications in basic molecular and cell biology research, as well as in gene therapy, adoptive immunotherapy, and stem cell therapy of cancer. Dr. Gelovani has authored more than 150 papers and delivered more than invited 200 lectures, including at a prestigious Novel Symposium in 2007.

Dr. Gelovani had organized the First International Symposium on Gene Imaging and Genetic Targeting of Radiation Therapy, Halkidiki, Greece, 1998, which started the “grass roots” movement to establish the Society for Molecular-Genetic Imaging (SMI). Dr. Gelovani is one of the co-founders of SMI. In 2001, at the Inaugural Meeting of SMI in Boston, Dr. Gelovani was awarded the first Achievement Award and a Gold Medal of the SMI for significant contributions to the field of Molecular Imaging. In 2003, Dr. Gelovani joined the UT MD Anderson Cancer Center, Houston, TX as a Professor and Chairman of the Department of Experimental Diagnostic Imaging and the Director of Center for Advanced Biomedical Imaging Research (CABIR). Dr. Gelovani has fostered the development of the Federation of Asian Societies for Molecular Imaging (FASMI) in 2006 and serves as the Advisor to the Secretary General of FASMI. In 2008-2009, Dr. Gelovani served as the President of the SMI. In 2009, he was the Organizer-In-Chief of the First World Molecular Imaging Congress (WMIC) in Nice, France. In 2009, Dr. Gelovani was elected to the Academy of Molecular Imaging (AMI) Board of Directors and became a President of AMI in September of 2010. For several years Dr. Gelovani has lead the process of merger of AMI and SMI to form the World Molecular Imaging Society (WMIS). Currently, Dr. Gelovani is the President of WMIS.

 

 

 Johannes Czernin

UCLA, School of Medicine

Department of Molecular and Medical Pharmacology

Division of Nuclear Medicine

Dr. Johannes Czernin got his MD in Medicine from the University of Vienna, Austria in 1983. He is currently Chief of the Ahmanson Biological Imaging Division, Professor of Molecular and Medical Pharmacology/Nuclear Medicine, Vice-Chair of the Department and Director of the Nuclear Medicine Division at the University of California, School of Medicine, Department of Molecular and Medical Pharmacology.

Dr. Czernin and his colleagues have established an exciting and well funded research environment, the Ahmanson Biological Imaging Division which has grown substantially over the last several years and consists of the Nuclear Medicine Clinic, a Clinical Imaging Research Program, and a new preclinical imaging center. The success of the division is based on extensive collaborations within the department of molecular and medical pharmacology and across several other departments including medicine, surgery, radiology, neurology, pathology and others.

Dr. Czernin in his capacity of Director of the Nuclear Medicine Clinic is responsible for multiple clinic sites within the UCLA Medical Center. The total number of clinical and research PET/CT scans performed approaches 4500/year. Conventional nuclear medicine services are offered at both Westwood and Santa Monica hospitals for more than 10,000 patients/year, Cardiac imaging sites in Santa Monical and Westwood serve close to 3,000 patients/year. Significant portions of the clinical revenue are invested in research programs within and outside the division.

Dr. Czernin was the President of the Academy of Molecular Imaging for 2 years and has been on the board of the Academy for the past 6 years. Over the past three years Dr. Czernin has been helped design and run the Sodium Fluoride Clinical for the Academy of Molecular Imaging. This is an on-going clinical trial that has 25 sites world-wide and currently has over 377 patients enrolled. The data from this trial will be used to help CMS and other payers make decisions about coverage for Sodium Fluoride.

 Anna Moore

 

Anna Moore holds a Ph.D. in Bioorganic Chemistry from the Russian Academy of Sciences, Moscow, Russia. She moved to the United States in 1990 and joined a Molecular Imaging Program at Massachusetts General Hospital/Harvard Medical School in 1991, first as a postdoctoral fellow and then as junior faculty. Currently, she is an Associate Professor in Radiology and a Director of the Molecular Imaging Laboratory at the Martinos Center for Biomedical Imaging, MGH/HMS. She is a member of the Affiliated Faculty of the Harvard-MIT Division of Health Sciences and Technology (Associate Professor). Her research deals with non-invasive imaging of molecular targets in cancer, diabetes and neurological disorders. She is a recipient of multiple grant awards from the NIH and other agencies. She publishes her research in high impact journals including Nature Medicine, Cancer Research, Diabetes, Radiology etc.

 

 Michael  F. Tweedle
Michael  F. Tweedle, PhD is the Stefanie Spielman Professor of Cancer Imaging and Professor of Radiology and Chemistry at the Ohio State University Medical School, The James Comprehensive Cancer Center, and theChemistry and Biochemistry Department in the School of Arts and Sciences, and Director of the Wright Center Molecular Imaging Agents  Laboratory.  His work experience in diagnostic imaging runs over twenty-five years. As a young research scientist at  NEN/DuPont Pharmaceuticals he invented catalystsforTc(III) radiopharmaceuticals, and created targeted 111In-molecular imaging agents from monoclonal antibodies. In 1986, working with E.R. Squibb and Sons, he invented and developed a novel first generation Gd-based MRI agent that is marketed internationally as ProHanceTM. He served as Director of Diagnostics R&D at Bristol-Myers Squibb, and then as President of Bracco Research USA Inc from 1994-2009, where he he and his team created two new MI agents: a peptide-targeted imaging/ radiotherapeutic (theranostic) for GRP-R+ prostate and breast cancer and a first in class angiogenesis VEGF-R2-targeted ultrasound diagnostic agent, now called BR55, both now in phase I clinical development. His current work includes molecular/cellular targeted Nuclear, MRI, US and Optical Imaging agents. He sits on the journal editorial boards of Magnetic Resonance Imaging and Investigative Radiology, has served on Expert Councils at the US Pharmacopeia, elected Boards of DirectorsofThe Society for Noninvasive Imaging in Drug Development, the Academy of Molecular Imaging and is currently an Officer and Board member of WMIS. He serves on the Scientific Advisory Boards of New York University, Macrocyclics Inc, Empirion LLC, and on the Board of Directors Novelos Pharmaceuticals Inc.  He has authored over 100 publications, including 31 patents and 19 book chapters and reviews.  In 2005 he was awarded The Harry Fischer Medal for Excellence in Contrast Media Research by the Contrast Media Research congress. 

 

 R Edward Coleman

R. Edward Coleman, M.D., is a Professor of Radiology and the Director of the Division of Nuclear Medicine at Duke University Medical Center.

He received his bachelor’s degree from the University of Evansville and a medical degree from Washington University. After serving an internship at the Washington University School of Medicine and subsequent residency at the Royal Victoria Hospital in Montreal, he returned to St. Louis in 1972 for a fellowship in nuclear medicine at the Mallinckrodt Institute of Radiology. After a short stent on the faculty there, he moved to the University of Utah as the Director of Nuclear Medicine. In 1979, he was appointed Professor of Radiology at Duke University Medical Center and subsequently was appointed Vice-Chairman of the Department of Radiology.

Dr. Coleman has participated in research in all aspects of nuclear medicine. He was at Mallinckrodt Institute of Radiology in the early 1970’s and participated in the performance of the first human PET studies. He has maintained a research and clinical interest in PET since that time. He has also been involved in the development and evaluation of SPECT imaging.

Dr. Coleman was a founder and first president of the Institute of Clinical PET (ICP) and a president of the Academy of Molecular Imaging (AMI). In 2007, he was awarded the Georg Charles de Hevesy Nuclear Pioneer Award from the Society of Nuclear Medicine.

 

 James Basilion

Dr. Basilion completed his BA in biochemistry at the University of Pennsylvania in 1984 and entered the doctoral program at the Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston. Following his graduate studies Dr. Basilion took a post-doctoral fellowship at the National Institutes of Health (NICHD) in the Cell Biology and Metabolism Branch with Dr. Richard Klausner. During his post-doctoral work he began a series of studies with investigators of the Center for Molecular Imaging Research at the Massachusetts General Hospital to exploit iron metabolism for molecular imaging. This work resulted in creation of a transgene and magnetic resonance imaging probes suitable for imaging gene transfer and changes in endogenous levels of internalizing receptors in vivo both non-invasively and in real time with MRI. In 1996 Dr. Basilion left the NIH to take a position as a Senior Scientist at a small genomics/anti-cancer biotech company. Dr. Basilion joined the Faculty of Harvard Medical School and Massachusetts General Hospital- Center for Molecular Imaging Research in 1999. While at MGH Dr. Basilion led a group of PhDs and physicians that were attempting to identify informative markers and molecular signatures of disease and develop imaging agents suitable to image simultaneous expression of multiple markers for breast, brain, and prostate cancers. In September 2005 Dr. Basilion joined the faculties of the Case School of Medicine and the Case School of Engineering as an Associate Professor and Director of the NFCR Center for Molecular Imaging at Case. Dr. Basilion is a member of several societies, has held several offices in the Society for Molecular Imaging, has written numerous reviews on molecular imaging and genomics and holds editorships on three imaging or imaging related journals. He is co-director of the Cancer Imaging Program at the Case Comprehensive Cancer Center and, most recently with a Stanford University collaborator, has co-founded Akrotome Imaging, a start-up biotech imaging company devoted to developing molecular imaging diagnostics.

 

 John Kotyk

John Kotyk received his Ph.D. in Chemistry in 1986 from Washington University (WU) in St. Louis, MO. Following a Postdoctoral Research Fellow position at WU focusing on development of new in vivo and in vitroNMR/imaging techniques, Dr. Kotyk joined the NMR Center in Monsanto’s Corporate Research Laboratories. At Monsanto his research efforts supported a diverse range of R&D programs in chemical, agricultural and pharmaceutical sciences. John held a variety of leadership positions in Discovery Research at Monsanto and during its merge with Pharmacia where he established the Biomedical Magnetic Resonance Laboratory (BMRL) to address pharmaceutical and agricultural R&D needs of the combined organization. Following Pharmacia’s subsequent acquisition by Pfizer, Inc., John continued managing the BMRL as a Research Fellow and led the preclinical MRI efforts within Pfizer’s Global Research and Development. Areas of research interests at Pfizer included development of preclinical imaging-based biomarkers to monitor in vivo disease progression/regression, and the evaluation of drug candidate efficacy, function, metabolism, and safety.

In November 2005, Dr. Kotyk joined the faculty of the Mallinckrodt Institute of Radiology at Washington University School of Medicine (WUSM) in St. Louis, MO, as a Research Associate Professor to help build the Center for Clinical Imaging Research (CCIR). Early in 2007, he became the Associate Director of the CCIR. Since then, he has also assumed responsibility as the Co-Director of the oncology Image Response Assessment Core (Siteman Cancer Center), and as the Co-Director of the Human Imaging Unit of the Institute of Clinical and Translational Sciences at WUSM. John’s current scientific interests focus on developing new imaging technologies and translating these into practice to expand and increase impact in clinical sciences.

 Jeff Bulte
Jeff W.M. Bulte is a Professor of Radiology at the Johns Hopkins University School of Medicine, with joint appointments in Biomedical Engineering and Chemical & Biomolecular Engineering. He serves as the Director of the Cellular Imaging Section in the Institute for Cell Engineering. Previously, he was a scientist at the National Institutes of Health, and obtained his Ph.D. degree Summa Cum Laude from the University in Groningen in The Netherlands.

 

 Klaas Nicolay
coming soon

 

 Zaver Bhujwalla
Zaver Bhujwalla, Ph.D. is a Professor in the Departments of Radiology and Oncology, and Director of the JHU ICMIC Program.  Her research has focused on the applications of MR imaging and spectroscopy and, more recently, multi-modality imaging, to understand and treat cancer.  A major focus of this effort is to understand cancer invasion and metastasis, and the role of the tumor microenvironment, vascularization and metabolism in these processes using noninvasive imaging, with the ultimate goal of finding effective means to reduce or prevent tumor metastasis from occurring.  Dr. Bhujwalla is a Fellow of the International Society of Magnetic Resonance in Medicine, and a Fellow of the American Institute of Biomedical Engineers.  Dr. Bhujwalla is associated with the editorial boards of Molecular Imaging, NMR in Biomedicine, Cancer Biology and Therapy, Contrast Media and Molecular Imaging.

 

 Rudin Markus
coming soon

 

Joseph Ackerman
Joseph J. H. Ackerman, Ph.D., is William Greenleaf Eliot Professor, Department of Chemistry, Washington University in Saint Louis  He holds joint appointments in Departments of Radiology and Internal Medicine, and is Laboratory Chief of Mallinckrodt Institute of Radiology’s Biomedical Magnetic Resonance Laboratory.  As Gold Medal Award recipient and Fellowof the International Society of Magnetic Resonance, he is a respected practitioner in the field of magnetic resonance as applied to intact biological systems.

An educator at Washington University in Saint Louis for the past three decades, Ackerman has trained and mentored numerous undergraduate, graduate, and postdoctoral students, many of whom now hold senior positions in academe and industry.  In addition to having oversight responsibilities for a laboratory whose members range from endowed-chair full professor to high school summer student, Ackerman’s own research efforts are broadly directed toward the development and implementation of MR imaging and spectroscopy techniques to provide a more complete understanding of the complex microstructure and governing biophysical, physiologic, and metabolic determinants of cells, tissues, and organisms in the intact, functioning state.

 

 Gary Luker
coming soon

 

 

Chrit Moonen

Chrit Moonen did his Masters in Molecular Sciences and his Ph.D. in biophysics (Wageningen University). He did part of his studies with Nobel Laureate Wüthrich in Zürich, Switzerland. He went for a postdoctoral period to the University of Oxford (Sir Georg Radda). He then worked at the University of California at Davis as a Visiting Research Scientist before becoming head of the NIH In Vivo NMR Research Center from 1987-1996. Then he moved back to Europe (Bordeaux, France) where he is Director of Research at the “National Center for Scientific Research (CNRS). He was director of the laboratory “Molecular and Functional Imaging: from Physiology to Therapy” from 2003-2011. He recently joined the Division of Imaging at the University Medical Center Utrecht to develop the theme of Molecular Imaging Guided Therapies. He coauthored over 150 scientific papers. He was President of the “International Society of Magnetic Resonance in Medicine” (2006), and of the “Society for Molecular Imaging” (2009). He received the European Magnetic Resonance Award 2000, is a Fellow of the International Society of Magnetic Resonance in Medicine, and of the European Society of Magnetic Resonance in Medicine and Biology. His recent work is mainly in molecular and cellular imaging, MRI guided Focused Ultrasound, and image guided control of gene expression and drug delivery.